This is in line with experimental research in rodents where central or peripheral administration of nmda - antagonists has been shown to produce effects that resemble some symptoms of schizophrenia . bilateral injections of competitive and non - competitive antagonists in the medial pfc ( mpfc ) induced hyperactivity 2 .实验中“ go ”线索呈现时， pfc神经元放电频率显著增加，高于“ no90 ”线索呈现时神经元放电频率增加值，提示对视觉警告信号的反应具有识别和分辨作用。
